Tetrachlorsalicylanilide (TCS) home ICD10: L23.9

Tetrachlorsalicylanilide (TCS)
Formule CAS
C13H7Cl4NO2 1154-59-2



Background
Tetrachlorsalicylanilide (TCS) is a bacteriostatic agent banned by the FDA from use in cosmetics.

Synonyms
3,3',4',5-Tetrachlorosalicylanilide
3,5-Dichloro-N-(3,4-dichlorophenyl)-2-hydroxybenzamide
Irgasan BS 200
TCS
Tetrachlorsalicylanilide

Uses
Cooling fluids
Deodorants
Polishes
Rinses
Shampoos
Surgical and laurndry soaps
Textile finishes

Cross-Reactions
Halogenated salicylanilides
Hexachlorophene

Unusual Reactions
Photoallergy
Phototoxicity
Persistent light reaction

Back to list of contact allergens


Referenties
1. Kaidbey, K.H. and A.M. Kligman, Photomaximization test for identifying photoallergic contact sensitizers. Contact Dermatitis, 1980. 6(3): p. 161-9.
2. Gerberick, G.F. and C.A. Ryan, Contact photoallergy testing of sunscreens in guinea pigs. Contact Dermatitis, 1989. 20(4): p. 251-9.
3. Shivji, G.M., W.R. Brown, and C.A. Ramsay, A dose-response study of UVB-induced suppression of contact photosensitivity in the mouse. British Journal of Dermatology, 1990. 122(2): p. 147-52.
4. Miyauchi, H. and T. Horio, A new animal model for contact dermatitis: the hairless guinea pig. Journal of Dermatology, 1992. 19(3): p. 140-5.



Author(s):
Allergology: background information on allergens.

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