Quinine sulfate home ICD10: L23.9


Formule CAS
(C20H24N2O2)2. H2SO4. 2 H2O 6119-70-6



Background
Quinine is an alkaloid obtained from the bark of various species of Cinchona trees. Quinine sulfate is an antimalarial agent and muscle relaxant. It is used for the prevention of nocturnal recumbency muscle cramps.

Synonyms
Quinine sulfate

Uses
Anti-malarial
Anti-pyretic
Bitter lemons
Muscle relaxant
Hair lotions
Pharmaceutical
Tonics

Cross-Reactions

Unusual Reactions
Photoallergy
Systemic contact dermatitis

Back to list of contact allergens


Referenties
1. Calnan, C.D., Photodermatitis and quinine sensitivity. Contact Dermatitis, 1978. 4(1): p. 58.
2. Hardie, R.A., et al., Quinine dermatitis: investigation of a factory outbreak. Contact Dermatitis, 1978. 4(3): p. 121-4.
3. Wahlberg, J.E. and A. Boman, Contact sensitivity to quinidine sulfate from occupational exposure. Contact Dermatitis, 1981. 7(1): p. 27-31.
4. Menz, J., S.A. Muller, and S.M. Connolly, Photopatch testing: a six-year experience [see comments]. Journal of the American Academy of Dermatology, 1988. 18(5 Pt 1): p. 1044-7.
5. Ljunggren, B., M. Hindsen, and M. Isaksson, Systemic quinine photosensitivity with photoepicutaneous cross-reactivity to quinidine. Contact Dermatitis, 1992. 26(1): p. 1-4.
6. Dias, M., I. Conchon, and T. Vale, Allergic contact dermatitis from quinine. Contact Dermatitis, 1994. 30(2): p. 121-2.
7. Isaksson, M., et al., Quinine and quinidine photoproducts can be identical. Acta Dermato-Venereologica, 1994. 74(4): p. 286-8.
8. Tapadinhas, C., et al., Contact dermatitis due to quinine-containing hair lotion. Contact Dermatitis, 1994. 31(2): p. 127.


Author(s):
dr. Jan R. Mekkes. Dermatologist, Amsterdam UMC.

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