| Formule |
CAS |
| C17H21ClN2S |
58-33-3 |
Background
Promethazine hydrochloride is an antihistamine and antiemetic.
SynonymsAtosil
Dimapp
Duplamin
Fargan
Fenazil
Ganphen
Lergigan
Phencen
Phenergan
Promethazine hydrochloride
Provigan
Prorex
Diphergan
Ganphen
Fellozine
Remsed
Dorme
Fenergan
Lergigan
Phencen
Phergan
Promantine
Promethegan
Promine
Protazine
Prothazin
Thiergan
Prorex
Prothazine
Provigan
Remsed
Vallgerine
N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine
10-(2-Dimethylaminopropyl)phenothiazine
10-(2-Dimethylamino-2-methylethyl)phenothiazine
N-(2´-dimethylamino-2´-methyl)ethylphenothiazine
Proazamine
RP 3277
RP 3389
Hiberna
Vallergine
UsesAnti-emetic pill, syrup, injection
Anti-cough syrup
Antihistamine
Cross-ReactionsPhenothiazines
Ethylenediamine hydrochloride
Para compounds
Chlorpromazine hydrochloride
Tripelennamine
Azo dyes
Unusual ReactionsErythema multiforme-like reactions
Photoallergy
Contact urticaria
Persistant light reaction
Back to list of contact allergens
Referenties
| 1. |
Suurmond, D., Patch test reactions to
phenergan cream, promethazine and triethanolamine.
Dermatologica, 1966. 133: p. 503. |
| 2. |
King, C.M. and M. Beck, Oral promethazine
hydrochloride in ethylenediamine-sensitive patients. Contact
Dermatitis, 1983. 9(6): p. 444-7. |
| 3. |
Wennersten, G., et al., The Scandinavian
multicenter photopatch study. Preliminary results. Contact
Dermatitis, 1984. 10(5): p. 305-9. |
| 4. |
Angelini, G., G.A. Vena, and C.L.
Meneghini, Allergic contact dermatitis to some medicaments.
Contact Dermatitis, 1985. 12(5): p. 263-9. |
| 5. |
Fisher, A.A., Lack of cross-reaction
between promethazine and ethylenediamine [letter]. Contact
Dermatitis, 1987. 16(4): p. 236. |
| 6. |
Menz, J., S.A. Muller, and S.M. Connolly,
Photopatch testing: a six-year experience [see comments].
Journal of the American Academy of Dermatology, 1988. 18(5 Pt
1): p. 1044-7. |
| 7. |
Edman, B., Computerized analysis of
concomitant contact allergens. Contact Dermatitis, 1991. 24(2):
p. 110-3. |
| 8. |
Holzle, E., et al., Photopatch testing:
the 5-year experience of the German, Austrian, and Swiss
Photopatch Test Group. Journal of the American Academy of
Dermatology, 1991. 25(1 Pt 1): p. 59-68. |
Author(s):
dr. Jan R. Mekkes. Dermatologist, Amsterdam UMC.
ICD10:
L23.9