Prilocaine hydrochloride home ICD10: L23.9

Prilocaine hydrochloride
Formule CAS
C13H21ClN2O 1786-81-8



Background
Prilocaine hydrochloride belongs to the amide group of local anesthetics and has been used since 1961. Allergic reactions are rare to members of this group of anesthetics.

Synonyms
Citanest
EMLA® cream
Prilocaine hydrochloride
Xylonest
N-(2-Methylphenyl)-2-(propylamino)-propanamide
2-(Propylamino)-o-propionotoluidide
N-(a-propylaminopropionyl)-o-toluidine
a-propylamino-2-methylpropionanilide
Propitocaine

Uses
Local anesthetic
EMLA® cream (lidocaine base + prilocaine base)

Cross-Reactions
Lidocaine
Bupivacaine
Cinchocaine
Mepivacaine

Unusual Reactions

Back to list of contact allergens


Referenties
1. Fregert, S., E. Tegner, and I. Thelin, Contact allergy to lidocaine. Contact Dermatitis, 1979. 5(3): p. 185-8.
2. Curley, R.K., A.W. Macfarlane, and C.M. King, Contact sensitivity to the amide anesthetics lidocaine, prilocaine, and mepivacaine. Case report and review of the literature. Archives of Dermatology, 1986. 122(8): p. 924-6.
3. Black, R.J., T.A. Dawson, and W.C. Strang, Contact sensitivity to lignocaine and prilocaine. Contact Dermatitis, 1990. 23(2): p. 117-8.
4. van den Hove, J., et al., Allergic contact dermatitis from prilocaine, one of the local anaesthetics in EMLA cream. Contact Dermatitis, 1994. 30(4): p. 239.


Author(s):
dr. Jan R. Mekkes. Dermatologist, Amsterdam UMC.

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