Prednisolone home ICD10: L23.9

Prednisolone
Formule CAS
C21H28O5 50-24-8



Background
Prednisolone is a corticosteroid. It has been classified as group A by Coopman et al. According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.

Synonyms
Prednisolone (11b)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
1,4-Pregnadiene-3,20-dione-11b,17a-21-triol
1,4-Pregnadiene-11b,17a,21-triol-3,20-dione
3,20-Dioxo-11b,17a,21-trihydroxy-1,4-pregnadiene
Metacortandralone
D1-Dehydrocortisol
D1-Hydrocortisone
D1-Dehydrohydrocortisone
Hydrodeltisone
Di-Adreson-F

Uses
Gluococorticoid
Corticosteroid
Anti-inflammatory
Pharmaceutical

Cross-Reactions
Tixocortol
Hydrocortisone
Prednisolone
Methylprednisolone
Meprednisone

Unusual Reactions

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Referenties
1. Coopman, S., H. Degreef, and A. Dooms-Goossens, Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. British Journal of Dermatology, 1989. 121(1): p. 27-34.
2. Dunkel, F.G., P. Elsner, and G. Burg, Allergic contact dermatitis from prednicarbate. Contact Dermatitis, 1991. 24(1): p. 59-60.
3. Rasanen, L. and T. Hasan, Allergy to systemic and intralesional corticosteroids. British Journal of Dermatology, 1993. 128(4): p. 407-11.
4. Lepoittevin, J.P., J. Drieghe, and A. Dooms-Goossens, Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids [see comments]. Archives of Dermatology, 1995. 131(1): p. 31-7.


Author(s):
dr. Jan R. Mekkes. Dermatologist, Amsterdam UMC.

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