Hexachlorophene home ICD10: L23.9

Hexachlorophene

Formula CAS
C13H6Cl6O2 70-30-4



Background
Hexachlorophene is used as a topical antiseptic. Because of potential neurotoxicity in humans, the FDA has regulated its use.

Synonyms
2,2´-Methylenebis[3,4,6-trichlorophenol]
2,2´-Dihydroxy-3,3´,5,5´,6,6´-hexachlorodiphenylmethane
bis(3,5,6-trichloro-2-hydroxyphenyl)methane AT-7
Bilevon
Dermadex
Exofene G-11
Gamophen
Hexachlorophene
Hexosan
pHisohex
Surgi-Cen
Surofene

Uses
pHisoHex
Soaps, cleansers, shampoos, and shaving cream.

Cross-Reactions
Bithionol
Halogenated salicylanilides

Unusual Reactions
Photoallergy

Back to list of contact allergens


Referenties
1. Fisher, A.A., F. Pascher, and N.B. Kanof, Allergic contact dermatitis due to ingredients of vehicles. A "vehicle tray" for patch testing. Archives of Dermatology, 1971. 104(3): p. 286-90.
2. Wilkinson, D.S. and E. Cronin, Contact dermatitis XIX. British Journal of Dermatology, 1972. 87(4): p. 400-2.
3. Iden, D.L. and A.L. Schroeter, The vehicle tray revisited: the use of the vehicle tray in assessing allergic contact dermatitis by a 24-hour application method. Contact Dermatitis, 1977. 3(3): p. 122-6.
4. Wilkinson, D.S., Hexachlorophene bath hazard [letter]. Contact Dermatitis, 1978. 4(3): p. 172.
5. Kaidbey, K.H. and A.M. Kligman, Photomaximization test for identifying photoallergic contact sensitizers. Contact Dermatitis, 1980. 6(3): p. 161-9.


Author(s):
Allergology: background information on allergens.

31-12-2015 (JRM) - www.skin-diseases.eu Terug naar homepagina