Diphenylmethane-4,4-diisocyanate (MDI)

Diphenylmethane-4,4-diisocyanate (MDI)

Formula	CAS
101-68-8	101-68-8

Background
Diphenylmethane-4,4-diisocyanate (MDI) is a raw material in polyurethane resins. The polyurethanes are of the thermosetting type of plastic and the polymerization is a polyaddition reaction. Diphenylmethane-4,4-diisocyanateis industrially used as crude MDI, which is a mixture of 4,4´-MDI with 2,4´-MDI and 2,2´-MDI. Crude MDI is aslo name polymethylene polyphenyl isocyanate.

Synonyms
Diphenylmethane-4,4-diisocyanate
MDI

Uses
Foam plastics
Paints
Polyurethane lacquers
Rubber and glues

Cross-Reactions

Unusual Reactions

Back to list of contact allergens

Referenties

1.	Liden, C., Allergic contact dermatitis from 4,4'diisocyanatol-diphenyl methane (MDI) in a molder. Contact Dermatitis, 1980. 6(4): p. 301-2.
2.	Estlander, T., et al., Occupational dermatitis from exposure to polyurethane chemicals. Contact Dermatitis, 1992. 27(3): p. 161-5.
3.	Rycroft, R.J.G., et al., Textbook of Contact Dermatitis. 1992, New York: Springer-Verlag.

Author(s):
Allergology: background information on allergens.

31-12-2015 (JRM) - www.skin-diseases.eu