Background
DNCB is a strong contact allergen and was used in the past for treatment of
alopecia areata. DNCB appeared to be a mutagenic compound, and is not longer
used in products for humans. For alopecia areata
diphenciprone (DPCP)
can be used.
SynonymsDNCB
Dinitrochlorobenzene
UsesTreatment of alopecia areata
Cross-Reactions
Unusual Reactions
Back to list of contact allergens
Referenties
| 1. |
Black HS, Castrow FF, Gerguis J. The
mutagenicity of dinitrochlorbenzene. Arch Dermatol
1985;121:348-349. |
| 2. |
Dunagin WG, Millikan LE.
Dinitrochlorobenzene immunotherapy for verrucae resistant to
standard treatment modalities. J Am Acad Dermatol 1982;6:40-45. |
| 3. |
Happle R. Hinweis zur DNCB-Therapie bei
Alopecia areata. Hautartz 1979;30:556. |
| 4. |
Happle R. The potential hazards of
dinitrochlorobenzene. Arch Dermatol 1985;121:330-332. |
| 5. |
Heid E, Grosshans E, Laplanche G,
Caussade P. Dinitrochlorobenzène. Usage thérapeutique Ann
Dermatol Venereol (Paris) 1984;111:841-849. |
| 6. |
Millikan L. Task force on DNCB reports
survey results. J Am Acad Dermatol 1982;7:91A-93A. |
Author(s):Allergology: background information on allergens.
ICD10: L23.9