Dichlorophene

Dichlorophene

Formula	CAS
	97-23-4

Background
Dichlorophene is a fungicide and bactericide used in dentifrices, shampoos, antiperspirant and deodorant creams, powder, toilet waters, and preparations for dermatophytosis of the foot. It is also used extensively as a mildewcide to treat and preserve cotton fibers, various fabrics, paper, synthetic leather lattices, and some adhesive tape backings. Dichlorophene is a more potent sensitizer than hexachlorophene. Although closely related chemically, they rarely cross-react. The U.S. Food and Drug Administration has restricted greatly the use of hexachlorophene for its possible toxic, but not allergic, effect.

Synonyms
2,2-Dihydroxydiphenylmethane
Antiphen
Cuniphen
Dicestal
Dichlorophen
Dichlorophene
Didroxane
G-4 (Compound G4)
Hyosan
Parabis
Teniathane
Teniatol
Westpuril

Uses
Bandages (soft casts)
Cosmetics
Dentifrices, toothpaste, and mouthwashes
Deodorants
Foot powders
Shampoos
Soaps and cleansers
Treated fabrics, papers, adhesives, and bandages

Cross-Reactions
Hexachlorophene

Back to list of contact allergens

Referenties

1.	Fisher, A.A. and I. Tobin, Sensitivity to compound G-4 ('Dichlorophene') in dentrifices. Journal of The American Medical Association, 1953. 151: p. 988.
2.	Epstein, E., Dichlorophene allergy. Annals of Allergy, 1966. 24: p. 437.
3.	Schorr, W.F., Dichlorphene (G-4) allergy. Archives of Dermatology, 1970. 102: p. 515.

Author(s):
Allergology: background information on allergens.

31-12-2015 (JRM) - www.skin-diseases.eu