| Formula |
CAS |
| C25H34O6 |
51333-22-3 |
Background
Budesonide is a nonhalogenated corticosteroid for use in topical preparations and for the treatment of rhinitis and asthma.
SynonymsBudesonide
16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione
(R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde
S-1320
Budeson
Preferid
Pulmicort
Rhinocort
Spirocort
UsesAnti-inflammatory agent
Nasal spray
Cross-ReactionsIt belongs to the group B (triamcinolone acetonide) grouping of corticosteroids (Coopman et al). According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.
Unusual Reactions
Back to list of contact allergens
Referenties
| 1. |
Gamboa PM, Jáuregui I, Antépara I. Contact dermatitis from budesonide in a nasal spray without cross-reactivity to amcinonide. Contact Dermatitis 1991;24(3):227-228. |
| 2. |
Hayakawa R, Matsunaga K, Suzuki M, Ogino Y, Arisu K, Arima Y, Hirose O. Allergic contact dermatitis due to budesonide. Contact Dermatitis 1991;24(2):136-137. |
| 3. |
Peris-Tortajada A, Giner A, Perez C, Hernandez D, Basomba A. Contact allergy to topical budesonide. J Allergy Clin Immunol 1991;87(2):597-598. |
| 4. |
Faria A, Marote J, de Freitas C. Contact
allergy to budesonide in a nasal spray. Contact Dermatitis
1992;27(1):57. |
| 5. |
Noda H, Matsunaga K, Noda T, Abe M, Ohtani T, Shimizu Y, Asahi K, Iida Y, Takigami N, Masutani M, et al. Contact sensitivity and cross-reactivity of budesonide. Contact Dermatitis 1993;28(4):212-215. |
| 6. |
Jorro G, Rochina A, Morales C, Burchés E, Peláez A. Contact allergy to topical budesonide in nasal spray. Contact Dermatitis 1993;28(4):254. |
| 7. |
Lepoittevin JP, Drieghe J, Dooms-Goossens A. Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids. Arch Dermatol 1995;131(1):31-37. |
Author(s):Allergology: background information on allergens.
ICD10: L23.9