Bioban CS 1246

Bioban CS 1246

Formula	CAS
C7H13NO2	7747-35-5

Background
Bioban CS 1246 is a preservative recommended for metal-working fluids. Patch-testing as a component of a standard series in 1480 consecutive patients revealed a reactivity of 0.9% (Bruze and Gruvberger). 8 of the 13 reacting patients were also allergic to formaldehyde. Bioban CS 1246 decompose to relase formaldehyde. An irritant reactions occurred in only 1 patient.

Synonyms
1-Aza-3,7-dioxa-5-ethyl-bicyclo-(3,3,0)-octane
5-ethyl-1-aza-3,7-dioxabicyclo-3,3,0-octane
Bioban CS 1246

Uses
Cooling fluids
Metalworking fluids
Preservative

Cross-Reactions
Formaldehyde

Unusual Reactions

Back to list of contact allergens

Referenties

1.	Dahlquist I. Contact allergy to the cutting oil preservatives Bioban CS-1246 and P-1487. Contact Dermatitis 1984;10(1):46.
2.	Bruze M, Gruvberger B. Contact allergy to Bioban CS 1246 in humans and guinea pigs. American Journal of Contact Dermatitis 1994;5(2): 88-89.

Author(s):
Allergology: background information on allergens.

31-12-2015 (JRM) - www.skin-diseases.eu