Betamethasone-17-valerate (Betnelan) home ICD10: L23.9

Betamethasone-17-valerate (Betnelan)

Formula CAS
C27H37FO6 2152-44-5



Background
Betamethasone-17-valerate is a high-potency topical fluorinated corticosteroid with low systemic effects. It has been classified as group D by Coopman et al. According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.

Synonyms
Betamethasone-17-valerate
Betnelan
Betnovate
Celestoderm-V

Uses
Topical and systemic corticosteroid

Cross-Reactions
Goup D Corticosteroids
Alclomethasone dipropionate
Betamethasone dipropionate
Betamethasone valerate
Clobetasone-17-butyrate
Clobetasone-17-propionate
Fluocortolone caproate
Fluocortolone pivalate
Fluprenidene acetate
Hydrocortisone-17-butyrate
Hydrocortisone-17-valerate

Unusual Reactions

Back to list of contact allergens

Referenties
1. Pasricha JS, Gupta R. Contact sensitivity to betamethasone 17-valerate and fluocinolone acetonide. Contact Dermatitis 1983;9(4):330-331.
2. Koch EM. Contact allergic reaction to valerate esters of betamethasone and hydrocortisone. Contact Dermatitis 1985;12(1):58.
3. Coopman S, Degreef H, Dooms-Goossens A. Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. Br J Dermatol 1989;121(1):27-34.
4. Dunkel FG, Elsner P, Burg G. Contact allergies to topical corticosteroids: 10 cases of contact dermatitis. Contact Dermatitis 1991 ;25(2):97-103.
5. Hisa T, Katoh J, Yoshioka K, Taniguchi S, Mochida K, Nishimura T, Kanetomo H, Kono T, Hamada T. Contact allergies to topical corticosteroids. Contact Dermatitis 1993;28(3):174-179.
6. Lepoittevin JP, Drieghe J, Dooms-Goossens A. Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids. Arch Dermatol 1995;131(1):31-37.


Author(s):
Allergology: background information on allergens.

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