| Formula |
CAS |
| C27H37FO6 |
2152-44-5 |
BackgroundBetamethasone-17-valerate is a high-potency
topical fluorinated corticosteroid with low systemic effects. It has been classified
as group D by Coopman et al. According the A-D grouping, patch-test reactions
occur 6-7 times more frequently within well-defined groups of structurally related
chemicals than between corticosteroids of different groups.
Synonyms
Betamethasone-17-valerate
Betnelan
Betnovate
Celestoderm-V
UsesTopical and systemic corticosteroid
Cross-ReactionsGoup D Corticosteroids
Alclomethasone dipropionate
Betamethasone dipropionate
Betamethasone valerate
Clobetasone-17-butyrate
Clobetasone-17-propionate
Fluocortolone caproate
Fluocortolone pivalate
Fluprenidene acetate
Hydrocortisone-17-butyrate
Hydrocortisone-17-valerate
Unusual Reactions
Back to list of contact allergens
Referenties
| 1. |
Pasricha JS, Gupta R. Contact sensitivity
to betamethasone 17-valerate and fluocinolone acetonide. Contact
Dermatitis 1983;9(4):330-331. |
| 2. |
Koch EM. Contact allergic reaction to valerate
esters of betamethasone and hydrocortisone. Contact Dermatitis 1985;12(1):58. |
| 3. |
Coopman S, Degreef H, Dooms-Goossens A.
Identification of cross-reaction patterns in allergic contact dermatitis
from topical corticosteroids. Br J Dermatol 1989;121(1):27-34. |
| 4. |
Dunkel FG, Elsner P, Burg G. Contact allergies
to topical corticosteroids: 10 cases of contact dermatitis. Contact
Dermatitis 1991 ;25(2):97-103. |
| 5. |
Hisa T, Katoh J, Yoshioka K, Taniguchi S,
Mochida K, Nishimura T, Kanetomo H, Kono T, Hamada T. Contact allergies
to topical corticosteroids. Contact Dermatitis 1993;28(3):174-179. |
| 6. |
Lepoittevin JP, Drieghe J, Dooms-Goossens
A. Studies in patients with corticosteroid contact allergy. Understanding
cross-reactivity among different steroids. Arch Dermatol 1995;131(1):31-37. |
Author(s):Allergology: background information on allergens.