| Formula |
CAS |
| C14H10O4 |
94-36-0 |
BackgroundBenzoyl peroxide is an antimicrobial
and keratolytic agent used in the treatment of acne. It is also present in foods.
It is a catalyst for cross-linking in the production of plastics and is occasionally
used in acrylic resin systems (eg. composite dental fillings, dental prothesis:
it is formed during the cross-linking process and will therefore not be mentioned
as a component of the resin system). It is used in stretching tapes used in
the treatment of leg ulcers. Benzoyl peroxide is metabolized in the skin to
benzoic acid. Positive patch tests to benzoyl peroxide may be explained by a
contact allergy to benzoic acid.
SynonymsAcetoxyl
Acnegel
Benzac
Benzaknen
Debroxide
Desanden
Benzagel 10
Benoxyl
Benzoyl peroxide
Benzoyl superoxide
Dibenzoyl peroxide
UsesAcne medications
Bone cement and dental acrylates
Dental
prosthesis
Flour Initiator in polymerization
Keratolytic Oils
Plastic
catalyst
Stretching tapes for leg ulcers
Cross-Reactions
Unusual ReactionsAirborne Discoloration of hair
Postinflammatory hyper- and hypopigmentation
Back to list of contact allergens
Referenties
| 1. |
Haustein UF, Tegetmeyer L,
Ziegler V. Allergic and irritant potential of benzoyl peroxide.
Contact Dermatitis 1985;13(4):252-257. |
| 2. |
Morelli R, Lanzarini M, Vincenzi
C, Reggiani M. Contact dermatitis due to benzoyl peroxide. Contact
Dermatitis 1989;20(3):238-239. |
| 3.. |
van Joost T, van Ulsen J,
Vuzevski VD, Naafs B, Tank B. Purpuric contact dermatitis to benzoyl
peroxide. J Am Acad Dermatol 1990;22(2 Pt 2):359-361. |
| 4. |
Bonnekoh B, Merk HF. Airborne
allergic contact dermatitis from benzoyl peroxide as a bleaching
agent of candle wax. Contact Dermatitis 1991;24(5):367-368 |
| 5. |
Dutrée-Meulenberg RO, Kozel
MM, van Joost T. Burning mouth syndrome: a possible etiologic role
for local contact hypersensitivity. J Am Acad Dermatol. 1992 Jun;26(6):935-40. |
| 6. |
Greiner D, WebeQuirce S. et
al. Occupational airborne contact dermatitis due to benzoyl peroxide.
Contact Dermatitis 1993;29(3):165-166. |
| 7. |
Kaufmann R, Boehncke WH. Benzoyl
peroxide as a contact allergen in adhesive tape. Contact Dermatitis
1999;41:233. |
Author(s):Allergology: background information on allergens.
ICD10: L23.9