Benzocaine home ICD10: L23.9

Benzocaine

Formula CAS
C9H11NO2 94-09-7



Background
Benzocaine is a p-aminobenzoic acid used as a local anesthetic. It belongs to the ester type anesthetics (procaine, benzocaine, tetracaine). Benzocaine-sensitive individuals do not react with lidocaine and other local anesthetics of the amide type.

Synonyms
4-Aminobenzoic acid ethyl ester
Aethoform
Americaine
Anesthone
Anesthesin
Benzocaine
Ethyl aminobenzoate
Ethyl-p-aminobenzoate
Orthesin
p-Aminobenzoic acid ethyl ester
Parathesin

Uses
Appetite suppressants
Adstringents and analgesics
Burn and sunburn remedies
Cough tablets, drops, and lozenges
Hemorrhoidal creams, suppositories, and enemas
Condoms
Oral and gingival products for teething, toothaches, canker sores, and denture irritation and in oral antibacterial agents
Podiatric products for athlete's foot, corns, calluses, and warts
Poison ivy products
Sore throat sprays and lozenges

Cross-Reactions
Butethamine
Hydrochlorothiazide
PABA and esters
Procainamide
Azo/aniline dyes
Paraphenylenediamine
Sulfonylureas
4-aminosalicylic acid
Parabens
Para compounds

Unusual Reactions
Photoallergy
Contact urticaria

Back to list of contact allergens


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Referenties
1. Maibach HI, Johnson HL. Contact urticaria syndrome. Contact urticaria to diethyltoluamide (immediate-type hypersensitivity). Arch Dermatol 1975;111(6):726-730.
2. Marzulli FN, Maibach HI. Contact allergy: predictive testing in man. Contact Dermatitis 1976;2(1):1-17.
3. Angelini G, Meneghini CL. Oral tests in contact allergy to para-amino compounds. Contact Dermatitis 1981;7(6):311-314.
4. Angelini G, Vena GA, Meneghini CL. Allergic contact dermatitis to some medicaments. Contact Dermatitis 1985;12(5):263-269.
5. Kreilgård B, Hansen J, Fischer T. Chemical, pharmaceutical and clinical standardization of the TRUE Test caine mix. Contact Dermatitis 1989;21(1):23-27.


Author(s):
Allergology: background information on allergens.

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