Amcinonide home ICD10: L23.9

Amcinonide

Formula CAS
C28H35FO7 51022-69-6



Background
Amcinonide is a high-potency topical and systemic corticosteroid. It has been classified as group B by Coopman et al. According the A-D grouping, patch-test reactions occur 6-7 times more frequently within well-defined groups of structurally related chemicals than between corticosteroids of different groups.

Synonyms
Amcinonide
21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene=3,20-dione cyclic 16,17-acetal with cyclopentanone, 21-acetate
CL-34699
Amciderm
Cyclocort
Penticort

Uses
Corticosteroid
Anti-inflammatory
Pharmaceutical

Cross-Reactions
budesonide, triamcinolone acetonide, fluocinonide, prednicarbate, hydrocortisone-17-butyrate.

Unusual Reactions

Back to list of contact allergens


Referenties
1. Boujnah-Khouadja A, et al. Allergy to 2 new corticoid molecules. Contact Dermatitis 1984;11(2):83-87.
2. Guin JD. Contact sensitivity to topical corticosteroids. Journal of the American Academy of Dermatology 1984; 10(5 Pt 1):773-782.
3. Hayakawa R, et al. Allergic contact dermatitis from amcinonide. Contact Dermatitis 1985;12(4):213-214.
4. Kubo Y, Nonaka S, Yoshida H. Contact allergy to amcinonide. Contact Dermatitis 1986;15(2):109-111.
5. Hayakawa R, et al. Contact dermatitis from amcinonide. Contact Dermatitis 1987;16(1):48-49. 6.
6. Sasaki E, et al. Contact dermatitis due to amcinonide. Contact Dermatitis, 1988;18(1):61-62.
7. Coopman S, Degreef H, Dooms-Goossens A. Identification of cross-reaction patterns in allergic contact dermatitis from topical corticosteroids. British Journal of Dermatology 1989;121(1):27-34.
8. Rivara G, Tomb RR, Foussereau J. Allergic contact dermatitis from topical corticosteroids. Contact Dermatitis 1989;21(2):83-91.
9. Hayakawa R, et al. Allergic contact dermatitis due to amcinonide. Contact Dermatitis 1990;23(1):49-50.
10. Dunkel FG, Elsner P, Burg G. Contact allergies to topical corticosteroids: 10 cases of contact dermatitis. Contact Dermatitis 1991;25(2):97-103.
11. Gamboa PM, Jauregui I, Antepara I. Contact dermatitis from budesonide in a nasal spray without cross-reactivity to amcinonide. Contact Dermatitis 1991;24(3):227-228.
12. Hisa T, et al. Contact allergies to topical corticosteroids. Contact Dermatitis 1993;28(3):174-179.
13. Noda H, et al. Contact sensitivity and cross-reactivity of budesonide. Contact Dermatitis 1993;28(4):212-215.
14. Lepoittevin JP, Drieghe J, Dooms-Goossens A. Studies in patients with corticosteroid contact allergy. Understanding cross-reactivity among different steroids. Archives of Dermatology 1995;131(1):31-37.


Author(s):
Allergology: background information on allergens.

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