| Formula |
CAS |
| C28H35FO7 |
51022-69-6 |
BackgroundAmcinonide is a high-potency topical and
systemic corticosteroid. It has been classified as group B by Coopman et al.
According the A-D grouping, patch-test reactions occur 6-7 times more frequently
within well-defined groups of structurally related chemicals than between corticosteroids
of different groups.
SynonymsAmcinonide
21-(Acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11b,16a,17,21-tetrahydroxypregna-1,4-diene=3,20-dione cyclic 16,17-acetal
with cyclopentanone, 21-acetate
CL-34699
Amciderm
Cyclocort
Penticort
UsesCorticosteroid
Anti-inflammatory
Pharmaceutical
Cross-Reactionsbudesonide, triamcinolone acetonide,
fluocinonide, prednicarbate, hydrocortisone-17-butyrate.
Unusual
ReactionsBack to list
of contact allergens
Referenties
| 1. |
Boujnah-Khouadja A, et al. Allergy to 2 new
corticoid molecules. Contact Dermatitis 1984;11(2):83-87. |
| 2. |
Guin JD. Contact sensitivity to topical corticosteroids.
Journal of the American Academy of Dermatology 1984; 10(5 Pt 1):773-782. |
| 3. |
Hayakawa R, et al. Allergic contact dermatitis
from amcinonide. Contact Dermatitis 1985;12(4):213-214. |
| 4. |
Kubo Y, Nonaka S, Yoshida
H. Contact allergy to amcinonide. Contact Dermatitis 1986;15(2):109-111. |
| 5. |
Hayakawa R, et al. Contact dermatitis from
amcinonide. Contact Dermatitis 1987;16(1):48-49. 6. |
| 6. |
Sasaki E, et al. Contact dermatitis due to
amcinonide. Contact Dermatitis, 1988;18(1):61-62. |
| 7. |
Coopman S, Degreef H, Dooms-Goossens A. Identification
of cross-reaction patterns in allergic contact dermatitis from topical
corticosteroids. British Journal of Dermatology 1989;121(1):27-34. |
| 8. |
Rivara G, Tomb RR, Foussereau J. Allergic
contact dermatitis from topical corticosteroids. Contact Dermatitis
1989;21(2):83-91. |
| 9. |
Hayakawa R, et al. Allergic contact dermatitis
due to amcinonide. Contact Dermatitis 1990;23(1):49-50. |
| 10. |
Dunkel FG, Elsner P, Burg G. Contact allergies
to topical corticosteroids: 10 cases of contact dermatitis. Contact
Dermatitis 1991;25(2):97-103. |
| 11. |
Gamboa PM, Jauregui I, Antepara I. Contact
dermatitis from budesonide in a nasal spray without cross-reactivity
to amcinonide. Contact Dermatitis 1991;24(3):227-228. |
| 12. |
Hisa T, et al. Contact allergies to topical
corticosteroids. Contact Dermatitis 1993;28(3):174-179. |
| 13. |
Noda H, et al. Contact sensitivity and cross-reactivity
of budesonide. Contact Dermatitis 1993;28(4):212-215. |
| 14. |
Lepoittevin JP, Drieghe J, Dooms-Goossens
A. Studies in patients with corticosteroid contact allergy. Understanding
cross-reactivity among different steroids. Archives of Dermatology
1995;131(1):31-37. |
Author(s):Allergology: background information on allergens.